Pregabalin (Lyrica) in the treatment of essential tremor
Identifieur interne : 002C58 ( Main/Exploration ); précédent : 002C57; suivant : 002C59Pregabalin (Lyrica) in the treatment of essential tremor
Auteurs : Theresa A. Zesiewicz [États-Unis] ; Christopher L. Ward [États-Unis] ; Robert A. Hauser [États-Unis] ; Jessica A. Pease Campbell [États-Unis] ; Kelly L. Sullivan [États-Unis]Source :
- Movement Disorders [ 0885-3185 ] ; 2007-01.
Descripteurs français
- Pascal (Inist)
English descriptors
- KwdEn :
- Aged, Anticonvulsants (therapeutic use), Dose-Response Relationship, Drug, Essential Tremor (drug therapy), Essential Tremor (physiopathology), Humans, Lyrica, Male, Middle Aged, Nervous system diseases, Pregabalin, Psychomotor Performance (drug effects), Treatment, Tremor, essential tremor, gamma-Aminobutyric Acid (analogs & derivatives), gamma-Aminobutyric Acid (therapeutic use), gamma‐aminobutyric acid, pregabalin, tremor.
- MESH :
- chemical , analogs & derivatives : gamma-Aminobutyric Acid.
- chemical , therapeutic use : Anticonvulsants, gamma-Aminobutyric Acid.
- drug effects : Psychomotor Performance.
- drug therapy : Essential Tremor.
- physiopathology : Essential Tremor.
- Aged, Dose-Response Relationship, Drug, Humans, Male, Middle Aged.
Abstract
We report on 2 essential tremor patients who experienced marked improvement in upper extremity tremor with the use of pregabalin (Lyrica, PGB). On PGB 200 mg/day, tremor amplitude was reduced by at least 40% in the worst affected hand in both patients as measured by accelerometry. Both patients also reported moderate reduction in tremor on the Clinical Global Impression Scale, and Fahn–Tolosa–Marin Part I scores were markedly improved. © 2006 Movement Disorder Society
Url:
DOI: 10.1002/mds.21211
Affiliations:
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Le document en format XML
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<front><div type="abstract" xml:lang="en">We report on 2 essential tremor patients who experienced marked improvement in upper extremity tremor with the use of pregabalin (Lyrica, PGB). On PGB 200 mg/day, tremor amplitude was reduced by at least 40% in the worst affected hand in both patients as measured by accelerometry. Both patients also reported moderate reduction in tremor on the Clinical Global Impression Scale, and Fahn–Tolosa–Marin Part I scores were markedly improved. © 2006 Movement Disorder Society</div>
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